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minocycline

Side Effect Search

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Minocycline may cause dizziness.

This drug may also cause the following symptoms that are related to dizziness:

Medical Source Information
Yellow highlights indicate symptoms related to dizziness.

Hypersensitivity side effects have included anaphylactoid reactions, anaphylactoid purpura, anaphylaxis (including shock and fatalities), angioneurotic edema, autoimmune vasculitis, drug fever, eosinophilic pneumonitis, erythema multiforme, fixed drug eruptions, hepatitis, lupus-like syndrome, myocarditis, pericarditis, polyarthralgia, pulmonary infiltrates with eosinophilia, rhabdomyolysis, serum sickness, serum sickness-like reactions, Stevens-Johnson syndrome, urticaria, and severe central nervous system-pulmonary hypersensitivity syndrome. Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome with persistent myocarditis has been reported in at least 3 cases.

Nervous system side effects have included headache, hypesthesia, paresthesia, sedation, vestibular reactions such as dizziness and vertigo. Additionally, rare cases of decreased hearing, tinnitus, and benign intracranial hypertension (pseudotumor cerebri), and bulging fontanels in infants have been reported.

Minocycline, like other tetracycline-class antibiotics, can cause fetal harm when administered to a pregnant woman. If any tetracycline is used during pregnancy or if the patient becomes pregnant while taking these drugs, the patient should be informed of the potential hazard to the fetus and treatment stopped immediately. Minocycline should not be used during pregnancy or during attempts to conceive by either males or females.

Minocycline has been associated with central nervous system side effects, included lightheadedness, dizziness, or vertigo. Patients should be cautioned against driving or performing hazardous tasks requiring coordination and mental alertness until they know how the drug affects them.

Tetracyclines have been associated with bulging fontanels in infants and benign intracranial hypertension (pseudotumor cerebri) in adults. Usual symptoms include headache and blurred vision and resolve upon discontinuation; however, permanent sequelae are possible.

Side Effects to Watch
Watch closely for the following side effects and notify your physician immediately should any of these develop:

Abnormal bruising or signs of bleeding such as bleeding from the gums, nose, digestive tract, vagina (females), faintness, dizziness, loss of consciousness, or rash (signs of problems with blood clot formation)

Lab and Diagnostic Tests
If certain symptoms develop, ask your physician whether you need the following lab tests or other diagnostic tests (if you've not already had them):

Blood tests to assess normal clotting - in people who develop signs of bleeding such as abnormal bruising or signs of bleeding including bleeding from the gums, nose, digestive tract, vagina (females), faintness, dizziness, loss of consciousness, or rash

References

Minocycline and benign intracranial hypertension. Donnet A, Dufour H, Graziani N, Grisoli F Biomed Pharmacother 1992;46:171-2.
Pseudo-tumor cerebri and acne. Delaney RA, Narayanaswamy TR Mil Med 1990;155:511.
Minocycline-induced central nervous system-pulmonary hypersensitivity syndrome. Settgast AM, Groth T, Gertner E Int J Dermatol 2003;42:316-7.
Minocycline and Pseudotumor cerebri: The well-known but well-kept secret. Weese-Mayer DE, Yang RJ, Mayer JR, Zaparackas Z Pediatrics 2001;108:519-20.
Product Information. Minocin (minocycline). Anonymous Lederle Laboratories, Wayne, NJ. PROD;
Minocycline and Pseudotumor cerebri: the well-known but well-kept secret. WeeseMayer DE, Yang RJ, Mayer JR, Zaparackas Z Pediatrics 2001;108:519-20.
Pseudotumor cerebri induced by minocycline treatment for acne vulgaris. Lewis PA, Kearney PJ Acta Derm Venereol 1997;77:83.
Minocycline treatment and pseudotumor cerebri syndrome. Chiu AM, Chuenkongkaew WL, Cornblath WT, Trobe JD, Digre KB, Dotan SA, Musson KH, Eggenberger ER Am J Ophthalmol 1998;126:116-21.
Arthralgias, myalgias, and autoimmune hepatitis with minocycline therapy. Matteson EL, Johnson BW, Maher JD J Rheumatol 1998;25:1653-4.
Minocycline and ototoxicity. Friedlander IR N Engl J Med 1979;1301:1450-1.
Minocycline and ototoxicity. Joy VA N Engl J Med 1979;301:1450.

Multum version: 154.0 (Jun 16, 2010)

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Frequent User Reported Side Effects

(4)	Hives
(4)	Drowsiness
(3)	Decreased alertness/consciousness
(3)	Headache
(2)	Itching
(2)	Yeast infections
(2)	Pseudotumor cerebri
(1)	Stretch marks on skin

Conditions Treated by minocycline

Drug Category

Tetracyclines

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