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Atropine may cause dry mucous membranes (common). This drug may also cause the following symptoms that are related to dry mucous membranes: Medical Source InformationYellow highlights indicate symptoms related to dry mucous membranes. General side effects have included hyperpyrexia, chest pain, excessive thirst, weakness, syncope, tongue chewing, dehydration, and feeling hot, Other general side effects include " atropine toxicity" ( anticholinergic side effects) which often present as fever, agitation, and dry skin/ mucous membranes. Dermatologic side effects have included dry mucous membranes, dry warm skin, flushed skin, oral lesions, dermatitis, petechiae rash, macular rash, papular rash, maculopapular rash, scarlatiniform rash, erythematous rash, sweating/ moist skin, cold skin, cyanosed skin and salivation. Inhibition of exocrine sweat glands has not usually been clinically significant except when perspiration is a major factor in body temperature control. Side Effects to Watch Watch closely for the following side effects and notify your physician immediately should any of these develop: - Abnormal heart rate, fluttering in the chest, weakness, faintness, dizziness or loss of consciousness (signs of a serious condition called "torsade de pointe or QT prolongation" in which irregular heartbeats occur)
Lab and Diagnostic Tests If certain symptoms develop, ask your physician whether you need the following lab tests or other diagnostic tests (if you've not already had them): - EKG - if abnormal heartbeats (rapid slow or irregular) develop
References - Periocular dermatitis from atropine. van der Willigen AH, de Graaf YP, van Joost T Contact Dermatitis 1987;17:56-7.
- Acute hypothermia associated with atropine. Lacouture PG, Lovejoy FH Jr, Mitchell AA Am J Dis Child 1983;137:291-2.
- Atropine toxicity in identical twins. Sanitato JJ, Burke MJ Ann Ophthalmol 1983;15:380-2.
- Product Information. Atropine Sulfate Injection, USP (atropine). Anonymous ESI Lederle Generics, Philadelphia, PA. PROD;
- Atropine and hyoscine. Shutt LE, Bowes JB Anaesthesia 1979;34:476-90.
- Contact allergy to atropine and other mydriatic agents. Yoshikawa K, Kawahara S Contact Dermatitis 1985;12:56-7.
- Product Information. AtroPen (atropine). Anonymous Meridian Medical Technologies Inc, Columbia, MD.
- Product Information. AtroPen (atropine). Anonymous Meridian Medical Technologies Inc, Columbia, MD.
Multum version: 154.0
(Jun 16, 2010)
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