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Yasmin (drospirenone-ethinyl estradiol) |
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Yasmin may cause headache. This drug may also cause the following symptoms that are related to headache:
Medical Source Information Yellow highlights indicate symptoms related to headache. Respiratory side effects have included upper respiratory infection, sinusitis, pharyngitis, sore throat, rhinitis, and bronchitis in postmarketing reports. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects: sudden numbness or weakness, confusion, pain behind the eyes, problems with vision, speech, or balance; chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling; a change in the pattern or severity of migraine headaches; stomach pain, loss of appetite, jaundice (yellowing of the skin or eyes); a breast lump; or symptoms of depression (sleep problems, weakness, mood changes). Less serious side effects may include: breast pain, tenderness, or swelling; freckles or darkening of facial skin, increased hair growth, or loss of scalp hair; changes in weight or appetite, swelling of your hands or feet; problems with contact lenses; vaginal itching or discharge; or changes in your menstrual periods. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088. Nervous system side effects have included chorea, which has been reported once in association with oral contraceptives. Headache and asthenia have been reported in postmarketing experience. Many of the adverse effects experienced by women on oral contraceptive combination products have been related to a relative excess or deficiency of the estrogen and progestin components of these formulations. The following categorizes many of the frequent adverse effects by relative excess or deficiency of these components. Progestin Excess: Acne, oily skin Breast tenderness Depression Tiredness, fatigue Hair loss Hypertension Increased appetite Weight gain Cholestatic jaundice Progestin Deficiency: Late breakthrough bleeding Amenorrhea Hypermenorrhea Estrogen Excess: Nausea Headache Melasma Hypertension Breast tenderness Edema Estrogen Deficiency: Early/mid-cycle breakthrough bleeding Increased spotting Hypomenorrhea Cardiovascular side effects of the estrogen component of this combination drug may be significant and have included hypertension. However, significant blood pressure increases generally occur only in women receiving high-dose estrogen products (50 mcg or more of ethinyl estradiol or equivalent daily). Estrogens have also been associated with edema. Other cardiovascular side effects have included aggravation of varicose veins. Some early investigations of women taking high dose estrogen combinations (50 mcg or more of ethinyl estradiol or equivalent daily) suggested that such women may be at increased risk of cardiovascular complications (myocardial infarction, stroke, and vascular thrombosis, including venous thromboembolism). However, more recent large investigations of women taking low dose estrogen combinations have suggested that oral contraceptive use is not associated with an increased risk of serious cardiovascular complications in healthy non smoking women up to the age of 45. (For women aged 35 to 44 who smoke or who have preexisting systemic diseases that may affect the cardiovascular system, use of oral contraceptives is not recommended.) However, some investigators have suggested that even the new low dose products may result in adverse effects on lipid metabolism and should prompt careful review of a woman's cardiovascular risk factors before a decision to use oral contraceptive combinations is made. The frequency of both subarachnoid hemorrhage and thrombotic stroke has been reported by some investigators to be higher in women taking oral contraceptive hormones. However, other investigators have suggested that the risk of these effects for women using newer low dose formulations are very small for young women without underlying cardiovascular disease or other risk factors. Use of drospirenone-ethinyl estradiol is contraindicated for women who have the following conditions: renal insufficiency, hepatic dysfunction, adrenal insufficiency, thrombophlebitis or thromboembolic disorders, a past history of deep-vein thrombophlebitis or thromboembolic disorders, cerebrovascular or coronary artery disease, known or suspected carcinoma of the breast, carcinoma of the endometrium or other known or suspected estrogen-dependent neoplasia, undiagnosed abnormal genital bleeding, cholestatic jaundice of pregnancy or jaundice with prior oral contraceptive use, liver tumor (benign or malignant) or active liver disease, and known or suspected pregnancy. The use of oral contraceptives is associated with increased risks of several serious conditions including myocardial infarction, thromboembolism, stroke, hepatic neoplasia, gallbladder disease, and hypertension, although the risk of serious morbidity or mortality is very small in healthy women without underlying risk factors. The risk of morbidity and mortality increases significantly in the presence of other underlying risk factors such as hypertension, hyperlipidemias, obesity and diabetes. Side Effects to Watch Watch closely for the following side effects and notify your physician immediately should any of these develop:
Lab and Diagnostic Tests If certain symptoms develop, ask your physician whether you need the following lab tests or other diagnostic tests (if you've not already had them):
References
Multum version: 154.0
(Jun 16, 2010)
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