
User Reviews \| Add Review \| Search Reviews	Drug Search

You have entered 0 Drug(s) and 0 Symptom(s)

Click Evaluate for a complete analysis of your drugs and symptoms

Crestor (rosuvastatin)

Side Effect Search

Underlined words or phrases provide helpful links to information in wikipedia.org and when moused over often give helpful definitions of the medical terms. Keywords

Crestor may cause low platelet count (may cause bleeding problems).

This drug may also cause the following symptoms that are related to low platelet count:

Medical Source Information
Yellow highlights indicate symptoms related to low platelet count.

Hematologic side effects including anemia and ecchymosis have been reported. Hematologic side effects including hemolytic anemia, thrombocytopenia, thrombotic thrombocytopenic purpura (TTP), and leukopenia have occurred with HMG-CoA reductase inhibitors. These effects may be manifestations of a hypersensitivity reaction.

Rosuvastatin is contraindicated in women who are or may become pregnant. By reducing cholesterol synthesis, rosuvastatin may cause fetal harm when administered to a pregnant woman. In addition, the benefit of treatment during pregnancy is unclear and the safety in pregnant women is unknown. The risks to the fetus and the lack of known clinical benefit during pregnancy should be explained to patients if they become pregnant while taking rosuvastatin.

Dipstick-positive proteinuria and microscopic hematuria have been seen with HMG-CoA use, more frequently in patients taking 40 mg of rosuvastatin. These findings were usually temporary and not associated with worsening renal function. While the clinical significance is unknown, a dose reduction should be considered for patients on rosuvastatin with unexplained persistent proteinuria and/or hematuria during routine urinalysis testing.

Caution should be exercised when anticoagulants are given in conjunction with rosuvastatin because of its potentiation of the effect of coumarin-type anticoagulants in prolonging the prothrombin time/INR. In patients taking coumarin anticoagulants and rosuvastatin concomitantly, INR should be determined before starting rosuvastatin and frequently enough during early therapy to ensure that no significant alteration of INR occurs.

Renal side effects including various forms of renal failure have been reported in patients taking rosuvastatin, although causality has not been determined. Patients who are candidates for statin therapy (e.g., patients with diabetes, hypertension, atherosclerosis, and/or heart failure) may also be at higher risk for kidney failure even when they are not taking statins. Proteinuria with or without hematuria has been reported during rosuvastatin therapy, and appears to be dose related.

Side Effects to Watch
Watch closely for the following side effects and notify your physician immediately should any of these develop:

Abnormal bruising or signs of bleeding such as bleeding from the gums, nose, digestive tract, vagina (females), faintness, dizziness, loss of consciousness, or rash (signs of problems with blood clot formation)
Muscle pain, weakness or tenderness (signs of a serious condition called "myopathy" in which muscle damage occurs)

Lab and Diagnostic Tests
If certain symptoms develop, ask your physician whether you need the following lab tests or other diagnostic tests (if you've not already had them):

liver function tests - check before starting treatment and then periodically
Creatine kinase - in people who develop muscle pain, weakness, or tenderness
inr - check before starting treatment
Blood tests to assess normal clotting - in people who develop signs of bleeding such as abnormal bruising or signs of bleeding including bleeding from the gums, nose, digestive tract, vagina (females), faintness, dizziness, loss of consciousness, or rash
liver function tests - at start of treatment and then every 6 months

References

Product Information. Crestor (rosuvastatin). Anonymous AstraZeneca Pharma Inc, Mississauga, ON.
Thrombotic thrombocytopenic purpura associated with statin treatment. Sundram F, Roberts P, Kennedy B, Pavord S Postgrad Med J 2004;80:551-2.

Multum version: 154.0 (Jun 16, 2010)

Add a User Review

To add a User Review fill out the fields below. A drug name is required to post. You will be asked to enter the dosage, which is listed on the bottle/container, along with units such as mg, ounces, etc; as well as how often you take the drug. When you enter a possible side effect, you will be asked about its severity. In the comment field, please describe your experiences or any comment that you will think help other users understand what they can expect from their drug treatment. We also welcome comments and suggestions about our site through feedback.

* Enter drug name- enter one drug at a time, by typing at least 3 letters of the drug name and select the appropriate drug from the list, then proceed to entering the next drug.

* Enter condition name - the "condition" is the reason you are taking the drug, which could be a disease such as "diabetes" or a symptom such as "joint aches". Enter a condition and select from the list shown, then enter the next condition if you are experiencing more than one.

* Enter side effects - these are any undesirable effects you might be experiencing from the drug(s). Enter your side effect and select from the list shown, then enter the next side effect if you are experiencing more than one. If you are not experiencing any side effects check the box below, No Side Effects.

No Side Effects

Enter comments - tell the community about your experiences and any information you may have about taking these drugs.

Age Gender:

Thank you for adding your review.

Return to Current Page

To help protect against automated posting, please enter the words that appear in the box below (more info).
Words should be separated by space.

Unable to see the image? (get another image)

* Required fields

NOTE: Just because a drug or combination of drugs can cause a symptom does not mean it is actually causing your symptom. Symptoms can be caused by medical conditions as well. Make sure that your physician is aware of any symptoms you are experiencing so he/she can work with you to determine the cause. Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: Please note that the information DoubleCheckMD.com provides is intended to help individuals to work with their medical professionals and is for educational purposes only. It does not constitute medical or healthcare advice and serves to supplement, not substitute for, the expertise and judgment of a healthcare professional. In all cases individuals should consult with a physician before taking any action based on DoubleCheckMD feedback including, but not limited to ceasing taking any drug, changing diet or commencing or discontinuing any course of treatment. The information provided by DoubleCheckMD.com is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that the use of a particular drug is safe, appropriate or effective.