My Drugs & SymptomsDrugsDrugs By ConditionTreatments
 User Reviews |  Add Review |  Search Reviews Drug Search
 

Summary of Symptoms

Drug withdrawal symptoms
Megace may cause drug withdrawal symptoms.
Inability to sit still/restlessness
Megace may cause a symptom that is related to inability to sit still/restlessness
Irritability
Megace may cause symptoms that are related to irritability

       
 
Drug withdrawal symptoms (develop when drug is stopped - may include agitation, restlessness, anxiety, depression, insomnia, tremor, increased blood pressure, nausea, abdominal cramps, blurred vision, seizures, sweating)
Megace (megestrol) may cause drug withdrawal symptoms.
Hide SOURCE +

Note: Original Source for Medical Professionals
Other side effects including a possible case of megestrol withdrawal syndrome have been reported.

REFERENCE +

  1. Product Information. Megace (megestrol). Anonymous Bristol-Myers Squibb, Princeton, NJ. PROD;
  2. Beneficial response to megoestrol acetate in AIDS-related cachexia and a possible megoestrol withdrawal-associated syndrome? Nathwani D, Green ST, Heslop JM, Goldberg DJ, Kennedy DH Acta Derm Venereol 1990;70:520-1.
 
       
 
       
 
Inability to sit still/restlessness
Megace (megestrol) may cause the following symptom that is related to inability to sit still/restlessness:
  • Drug withdrawal symptoms
Hide SOURCE +

Note: Original Source for Medical Professionals
Other side effects including a possible case of megestrol withdrawal syndrome have been reported.

REFERENCE +

  1. Product Information. Megace (megestrol). Anonymous Bristol-Myers Squibb, Princeton, NJ. PROD;
  2. Beneficial response to megoestrol acetate in AIDS-related cachexia and a possible megoestrol withdrawal-associated syndrome? Nathwani D, Green ST, Heslop JM, Goldberg DJ, Kennedy DH Acta Derm Venereol 1990;70:520-1.
 
       
 
       
 
Irritability
Megace (megestrol) may cause the following symptoms that are related to irritability:
  • Drug withdrawal symptoms.
  • Increased feeling of stress
Hide SOURCE +

Note: Original Source for Medical Professionals
Other side effects including a possible case of megestrol withdrawal syndrome have been reported.

Caution is advised that their is a significant risk to develop blood clots, particularly in cancer patients and others susceptible to clotting.

The glucocorticoid activity of megestrol has not been fully evaluated. Clinical cases of new onset diabetes mellitus, exacerbation of preexisting diabetes mellitus, and overt Cushing's syndrome have been reported in association with chronic use of megestrol. Clinical cases of adrenal insufficiency have also been reported in patients receiving or being withdrawn from chronic megestrol therapy. Adrenocorticotropin (ACTH) stimulation testing has revealed the frequent occurrence of asymptomatic pituitary-adrenal suppression in patients treated with chronic megestrol therapy. Therefore, the possibility of adrenal insufficiency should be considered in any patient receiving or being withdrawn from chronic megestrol therapy who presents with symptoms and/or signs suggestive of hypoadrenalism (e.g. hypotension, nausea, vomiting, dizziness, or weakness) in either the stressed or non-stressed state. Laboratory evaluation for adrenal insufficiency and consideration of replacement or stress doses of rapidly acting glucocorticoid are strongly recommended in such patients. Failure to recognize inhibition of the hypothalamic-pituitary-adrenal axis may result in death.

In patients who are receiving or being withdrawn from chronic megestrol therapy, consideration should be given to the use of empiric therapy with stress doses of a rapidly acting glucocorticoid in conditions of stress or serious intercurrent illness.

REFERENCE +

  1. Product Information. Megace (megestrol). Anonymous Bristol-Myers Squibb, Princeton, NJ. PROD;
  2. Beneficial response to megoestrol acetate in AIDS-related cachexia and a possible megoestrol withdrawal-associated syndrome? Nathwani D, Green ST, Heslop JM, Goldberg DJ, Kennedy DH Acta Derm Venereol 1990;70:520-1.
 
       
 
 
NOTE: Just because a drug or combination of drugs can cause a symptom does not mean it is actually causing your symptom. Symptoms can be caused by medical conditions as well. Make sure that your physician is aware of any symptoms you are experiencing so he/she can work with you to determine the cause. Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: Please note that the information DoubleCheckMD.com provides is intended to help individuals to work with their medical professionals and is for educational purposes only. It does not constitute medical or healthcare advice and serves to supplement, not substitute for, the expertise and judgment of a healthcare professional. In all cases individuals should consult with a physician before taking any action based on DoubleCheckMD feedback including, but not limited to ceasing taking any drug, changing diet or commencing or discontinuing any course of treatment. The information provided by DoubleCheckMD.com is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that the use of a particular drug is safe, appropriate or effective.


 
Please enter a name for this evaluation.
Example: Grandma's evaluation, Sore legs, Bruising and prozac
 
 
 
 
You are about to logout but your evaluation has not been saved. Would you like to save your evaluation?
 
 
 
 
We will notify you be email when we recieve any new data on the information you’ve provided for this evaluation.
 
 
     
 
 
     
 
 
Close CLOSE WINDOW

HOLDER
 
 
 
     
 
 
 
Close CLOSE WINDOW
HOLDER
 
 
   
 
     
 
 
     
     
 
 
     
 
My Saved Evaluations Close
 
 
  Date       Name       Delete  
  You have no saved evaluations.   
 
     
 
 
Username
Password
 
Forgot Password Log into DoubleCheckMD
 
 
 
Email Address
 
 
 
 
 
 
We'll keep Your Personal Information Private

Registration helps ensure the privacy of your personal health information. It's easy to register. Just enter a username and password. This is information you will use to login so you may want to write it down.
Username*
Password*
Password* (verify)
First Name (optional)
Last Name (optional)
Email Address (optional)
I have read and agree to abide by the DoubleCheckMD Terms of Use and DoubleCheckMD Privacy Policy.
I am a medical professional
 
Register
 
 
First name
Last name
Email Address
Comments*
 
 
 
First name
Last name
Email Address
Comments*